Wilmington Chamber of Commerce | 6,916 followers on LinkedIn. We position the community for prosperity by encouraging business growth. | The Wilmington Chamber of Commerce is distinguished as the first and longest continually operating chamber of commerce in North Carolina. Our chamber maintains a 154 year legacy of protecting and strengthening the Wilmington business community and helping businesses grow and thrive. We connect over 800 members consisting of businesses large and small, representing more than 40,000 employees in southeastern North Carolina.