Macrene Actives | 495 followers on LinkedIn. An all-in-one, toxin-free anti-aging luxury skin care solution created by renowned dermatologist Dr. Macrene Alexiades. | Macrene Actives is an all-in-one, toxin-free anti-aging luxury skin care solution for all skin types created by Macrene Alexiades, a board-certified dermatologist in both New York City and the EU.