Institute for Systems Biology (ISB) | 12,092 followers on LinkedIn. Science Transforming Health | ISB is a collaborative and cross-disciplinary non-profit biomedical research organization based in Seattle. We focus on some of the most pressing issues in human health, including aging, cancer, COVID, the gut microbiome, and many chronic and infectious diseases. Our science is translational, and we champion sound scientific research that results in real-world clinical impacts.