CRISP - Chesapeake Regional Information System for our Patients | 2,549 followers on LinkedIn. CRISP is a regional health information exchange (HIE). | CRISP is a regional health information exchange (HIE) serving Maryland and the District of Columbia. We are a non-profit organization advised by a wide range of stakeholders who are responsible for healthcare throughout the region. CRISP has been formally designated as Maryland's statewide health information exchange by the Maryland Health Care Commission.